Aging


Can we really cure ageing? David Sinclair thinks so, and he’s going to try to prove it.

David Sinclair is a scientist and entrepreneur working on increasing human health, productivity, and lifespan. After co-discovering a molecular cause of aging at the Massachusetts Institute in Boston in the mid-1990s, he joined the faculty of Harvard Medical School where he is now a tenured Professor. In 2005, he founded the Glenn Laboratories for Aging Research at Harvard and serves as their Co-Director. He is also a Professor at the Lowy Cancer Centre at the University of New South Wales, Sydney.

His research is aimed at understanding why we grow old and using this knowledge to prevent and treat both rare and common diseases. He is perhaps best known for identifying resveratrol from red wine as an anti-aging molecule. He has founded four biotechnology companies; to treat age-related diseases (Sirtris), improve female reproductive health and IVF (OvaScience), treat type 2 diabetes (Cohbar), and develop vaccines against malaria, chlamydia, tuberculosis, pneumonia, and cancer (Genocea).

In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)

Comments

  1. Singularity 2045 says

    +33rd Square wrote: “Sinclair has also worked on research to redefine what
    aging is. Previously aging was thought to be brought about by accumulating
    genetic mutations in our cells. Now, it has been shown that the process
    may be the result (or at least partially the result of) of a buildup of
    chemicals that turn certain genes on. This epigenetic change may be
    reversible.”
    http://www.33rdsquare.com/2013/07/david-sinclair-talks-about-aging.html

  2. James Clement says

    An inspiring plea for finding a cure for aging, by Harvard Medical School
    professor, David A. Sinclair. This is one of the reasons I really like
    David – he stands out from many researchers because he actually wants to
    cure aging, not just get grants and publish papers!

  3. Jennifer Linsky says

    +33rd Square wrote: “Sinclair has also worked on research to redefine what
    aging is. Previously aging was thought to be brought about by accumulating
    genetic mutations in our cells. Now, it has been shown that the process
    may be the result (or at least partially the result of) of a buildup of
    chemicals that turn certain genes on. This epigenetic change may be
    reversible.”
    http://www.33rdsquare.com/2013/07/david-sinclair-talks-about-aging.html

  4. Hanne Lykke Poulsen says

    Of course the medical industry wanted to silence him and shut off funding
    for science into delaying ageing – Cos ageing and disease is what the
    medical industry earns their money on!

  5. Fred Berger says

    I’m tired of mainstream medicine NOT considering aging a disease. Of course
    it’s a disease. Just because a certain degenerative condition effects
    EVERYONE doesn’t mean it’s NOT a disease. Thank you Dr. Sinclair for taking
    one this project.

  6. Vera Thomson says

    David, How could this company discount your research? For them to be
    able to do this they would have to show proof? Could your elaborate more
    on that one. I really think your research is amazing b ut I need to know
    how what you said happened because of the other company discounting your
    work really could happen.vera

  7. T Oadaly says

    If someone invents a cure for aging, they’ll be the world’s first
    trillionaire. It seems like there’s a tremendous financial incentive, yet
    it’s being mostly ignored.

  8. Ice says

    David Sinclair really brushed over the whole part where the Pharmaceutical
    companies said he had it all wrong. How was he wrong? Did they prove that
    Sirtuins are simply snake oil or did they falsely just say that we should
    not research aging? There are so many questions left unanswered. It would
    be nice if he would have addressed that in a little greater detail. Was he
    to embarrassed to address it or was it just a failed chance to explain the
    history of this research???

  9. Rossi R says

    Just wondering- these researchers work for institutions found and funded by
    the illuminati. The same ones interested in keeping the population count
    down. How much of the research is going to make it to the masses and
    benefit society (even if valid results are found?) Something to think
    about!

  10. Betty Berry says

    David Sinclair is a Mighty man of biology in my mind, he is taking on the
    worst plague ever to hit mankind, aging! But, there is only one man who
    knows the causes and now soon cure for aging and premature death! Read past
    commentary… There is one man who has found the causes and now soon cure
    for the pandemic plague called aging and premature death! Go to the pasted
    commentary copied just now from a piece on can science end aging! The
    answer is yes! Yes, Science has been destined to end aging! Go to the site
    at Adam and Eve Word Research blog spot, and therein the word researcher
    explains how science has had the means to end aging and premature death now
    for many years! On the site below the plea for funds, are many given ways
    of aging the pandemic plagues attack upon mankind! The Researcher has
    already located the molecules, he merely needs laboratories and funds to
    formulate the cure for Aging and premature death, the rampant plague upon
    mankind/wo-mankind! Respect

  11. Romy Jugroo says

    In my opinion,other ways of living longer, besides the great advice given,
    are to spend less, work less,walk more, sleep more to name a few.

  12. Sidney Dobber says

    Improving the quality of life seems the right thing to me, not necessarily
    the length of live! The thing is we will die of a failure of some organ. A
    heart stopping is not a disease, an old person is not ugly and ageing is
    not a bad thing.

  13. Paul J says

    I don’t know why the aging process is such a mystery. I mean, what
    really causes aging?? I know there are theories, but does anyone know for
    sure? There has to be a reason, people don’t just age for no reason. If
    theres no found reason for aging, then its like saying that aging occurs as
    if by something supernatural, or magic, which, in my opinion, is absurd. 

  14. David Fuchs says

    *A Cure for Ageing?: David Sinclair at TEDxSydney*

    David Sinclair is a scientist and entrepreneur working on increasing human
    health, productivity, and lifespan. After co-discovering a molecular cause
    of aging at the Massachusetts Institute in Boston in the mid-1990s, he
    joined the faculty of Harvard Medical School where he is now a tenured
    Professor. In 2005, he founded the Glenn Laboratories for Aging Research at
    Harvard and serves as their Co-Director. He is also a Professor at the Lowy
    Cancer Centre at the University of New South Wales, Sydney.

    His research is aimed at understanding why we grow old and using this
    knowledge to prevent and treat both rare and common diseases. He is perhaps
    best known for identifying resveratrol from red wine as an anti-aging
    molecule. He has founded four biotechnology companies; to treat age-related
    diseases (Sirtris), improve female reproductive health and IVF
    (OvaScience), treat type 2 diabetes (Cohbar), and develop vaccines against
    malaria, chlamydia, tuberculosis, pneumonia, and cancer (Genocea).

    In the spirit of ideas worth spreading, TEDx is a program of local,
    self-organized events that bring people together to share a TED-like
    experience. At a TEDx event, TEDTalks video and live speakers combine to
    spark deep discussion and connection in a small group. These local,
    self-organized events are branded TEDx, where x = independently organized
    TED event. The TED Conference provides general guidance for the TEDx
    program, but individual TEDx events are self-organized.* (*Subject to
    certain rules and regulations)

    A Cure for Ageing?: David Sinclair at TEDxSydney

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